For over two decades Roland Martin and Mireia Sospedra have been pursuing research about the disease mechanisms and target antigens in MS. Andreas Lutterotti joined the research team in 2006 and has been instrumental in the development of a semi-automatic GMP process to couple autologous red blood cells with peptides and early attempts at antigen-specific tolerance induction.

The founders: Andreas Lutterotti, Mireia Sospedra, Roland Martin

Cellerys was founded in 2015 as a spinoff from the University of Zurich, where it conducted a successful phase I clinical trial with the support of Wyss Zurich, a joint accelerator of the University of Zurich and ETH Zurich (Swiss Federal Institute of Technology Zurich). The phase I trial showed excellent tolerability and safety and indicated the induction of several tolerance mechanisms.

In 2021, Cellerys entered into partnership with Novartis to support the Phase Ib trial for an immune tolerization therapy (CLS12311) in multiple sclerosis. This phase Ib trial (RED4MS) has now been finalized and has demonstrated the safety and tolerability of this innovative tolerance induction therapy. The treatment is now ready to enter into Phase IIa trial.

Leadership

Clinical/Regulatory Team

Lab Team

Magdalena Foege, Andreas Lutterotti, Nicola Rennie, Nathalie Fournichot, Laure Tillé, Roland Martin, Mireia Sospedra, Zoe Marti, Valentin von Niederhäusern, Nik Barbet, Jacobo Sarabia del Castillo, Yvonne Sturm

Board of Directors